Tranexamic acid aur Mefenamic Acid

Introduction aur Indication

Tranexamic acid aur Mefenamic Acid ke alawa bhi bahut saare trade naam hain jo ek anti-inflammation medication ke roop mein upyog mein laaye jaate hain. Is medication ke teen upyog hain jo sahiankaara mein laaye jaate hain. Pehla upyog sahi dard ke liye hai, dusra upyog alag-alag types ke bleeding ko rokne ke liye hai aur teesra upyog heavy bleeding ko rokne ke liye hai. Ye dono drugs ek hi bahut khas combination mein jaane jaate hain. Is combination ko scientists ne acute bleeding ke upchaar mein develop kiya hai.

Mechanism of Action

Tranexamic acid aur Mefenamic Acid ek opioid drugs ke aadhaar par kaam karte hain. Ye dono bleeding ko rokne ke liye kaam karte hain. Tranexamic Acid khaane ke baad intestine mein jakar body mein absorb hota hai aur kaam karta hai. Iss mein shaamil hain chemical changes jis se jodo ke muscles aur blood vessels ko halka karke pehlaansh karne ke liye taiyaar kiya jaata hai. Mefenamic Acid ek NSAID hota hai jo arthritis ke saath saath alag-alag types ke dard ko kam karne ka kaam karta hai.

Kitne Dino Mein Kaam Karna Shuru Ho Jaata Hai?

Tranexamic Acid aur Mefenamic Acid dono ek doosre se alag-alag tarah ke drugs hain aur unki action ko alag tarah ka time lagega. Tranexamic Acid mein action shuru hone ka time range ke dekhne mein daal diya ja sakta hai, jismein 3 se 12 hours ke beech ka samay ho sakta hai. Jaise he Tranexamic Acid body mein absorb hota hai woh kaam shuru ho jaata hai. Mefenamic Acid ki bhi alag range hai jo ki 1 se 6 hours ke beech mein ho sakti hai.

Absorption, Route aur Elimination

Tranexamic Acid ek intravenous ya oral route se liya ja sakta hai aur achha tarah se body mein absorb hota hai aur bahut kam waqt mein iska pura bloodstream mein circulate ho jaata hai. Iss drug ko primarily kidneys mein metabolize kiya jaata hai, jismein 90% drug metabolites mein elimination hote hue urine se nikal jaate hain. Mefenamic Acid bhi ek oral route se liya ja sakta hai aur achha tarah se absorb hota hai. Iska dose mein se 80% metabolites mein urine se bahar jaate hain.

Dose, Administration, Side effects, Toxicity, aur Precaution

Tranexamic Acid aur Mefenamic Acid dono ek doosre ke saath combination mein bahut kam aaj ka zamana mein upyog ke liye kiya jaata hai. Tranexamic Acid ki ek fixed dose hai jo ki 1 gram per day divide mein paanch antarite mein liya ja sakta hai 3-4 doses mein aur ye intramuscular ya intravenous route se liya ja sakta hai. Mefenamic Acid ki ek fixed dose hai jo ki 500 milligram per day divide mein do antarite mein liya ja sakta hai aur ye oral route se liya ja sakta hai. Safety ke liye in dono drugs ki kuch side effects hai jo ki dast ya pet mein dard, hichki, bukhaar, chakkar hona, dast mein sujan, ya ek normal cold jaisi kai symptoms mein se kuch hain. Iska bhi saaf reaction nahin hota hai, lekin iska overdose karke bahut saari problems ho sakti hain jo ki iska toxicity, death, vomiting, ya kidney aur liver problems jaise kai khatraat include karte hain. Iss liye ye dono drugs ke sath kaafi acche precaution aur medical advice ikaththa kiya jaana jaroori hai.

Interaction, Disease interaction, Drug interaction, Food interaction, aur Pregnancy Use

Tranexamic Acid aur Mefenamic Acid dono alag-alag tarah ke interaction ho sakte hain. Iske use mein ya fir combination mein iska koi bhi reaction aa sakta hai jo ki drugs aur disease interaction ke liye khatra ka kaaran ban sakta hai. Iske alawa bhi food aur medication ke saath bhi iska koi reaction bhi ho sakta hai, jaise ki fruits aur dairy products iss drug ke saath jyaada reaction mein aa sakte hain. Iss drug ka use pregnant women mein bahut savdhani se kiya jaana chahiye kyoki iske use ke gambhir side effects ho sakte hain. Lactation mein bhi Tranexamic Acid aur Mefenamic Acid dono combination mein use na kare.

Acute Overdose, Contraindication, Usage Direction, Storage Condition

Iss combination mein Tranexamic Acid aur Mefenamic Acid dono ka overdose bahut khatraanak ho sakta hai. Iska overdose anaemia ya fir thrombotic abnormalities ki wajah se bhi ho sakta hai. Iss drug ka use iske contraindication ke saath- saath kisi bhi heart problem ke patient mein na kiya jaaye. Iske saath hi iska upyog puri tarah se physicians dvaara diye gaye instruction ke upar bhi kiya jaana chahiye taaki side effects ki taraf se koi problem na ho. Isko bina storage condition mein rakhne par bhi use na kiya jaaye.

Volume of Distribution, Half Life, Clearance

Tranexamic Acid aur Mefenamic Acid dono drugs organism mein half life ke dekhne mein alag-alag hain. Tranexamic Acid ki half life 5-7 hours mein hoti hai aur ye aapke body mein 1-2 hours mein circulate ho jaati hai. Mefenamic Acid ki half life 8-12 ke beech mein hoti hai aur ye body mein 1-2 hours mein circulate ho jaati hai. Iske alawa ye dono drugs ke volume of distribution alag-alag hain, Tranexamic Acid ki volume of distribution 70 litre mein hoti hai aur Mefenamic Acid ki volume of distribution 7-10 litre mein hoti hai. Aur iske alawa ye dono drugs ki clearance alag-alag hain. Tranexamic Acid ki clearance 7-11 ml/min hoti hai aur Mefenamic Acid ki clearance 1-2 ml/min hoti hai.

Hindi Mai Generic Name

Tranexamic Acid - त्रानेक्सामिक अश्रु
Mefenamic Acid - मेफेनामिक अश्रु

Here you find in details version of Tranexamic Acid + Mefenamic Acid