Hydroquinone, Mometasone Furoate aur Tretinoin

Introduction

Hydroquinone, mometasone furoate aur tretinoin ek aise combination hain jo skin ko saaf karne aur skin dark spots ko hatane Ke Liye doctor dwara diya gaya hain. iska Use dark spots, hyperpigmentation, melasma, aur kabhi kabhi acne aur sun tan ke Liye kiya jata hai.

Indication

Hydroquinone, mometasone furoate aur tretinoin ek aisa combination hai jo dark spots, hyperpigmentation, melasma, aur acne aur sun tan ko kam karne ke liye diya jata hai.

Mechanism of Action

Hydroquinone se Tyrosinase enzyme ko block kiya jata hai jis se melanin ka production ya production kam hota hai. Mometasone Furoate se inflammation aur itching kam karne ke Liye istemal kiya jata hai. Tretinoin se Ek topically majbut layer ki formation hoti hai jo skin ko difficulti se retain karne mai madad karta hai.

How Long Does it Take To Work?

Aapki skin par is combination se needha asar najar aana shuru ho jata hai, par uski puri achhi result dekhne ke Liye 3-4 month ko take lena padta hai.

Absorption

Gale mai use hone wale combination ka absorption badh jata hai. is combination mai Hydroquinone ka absorption 40-60%, Mometasone ka absorption 55-76%, aur Treotine ka absorption 60-90%.

Route of Elimination

Hydroquinone kidney aur liver se puri tarah eliminated ho jata hai. Mometasone Furoate ka elimination renal aur fecal route se hota hai. Tretinoin ka elimination aksar faecal route se hi hota hai.

Dosage

Hydroquinone- 2%–4% Mometasone Furoate- 0.1%–0.2% Tretinoin- 0.025%–0.05%.

Administration

Gale mai is combination ko roz subah aur raat ko clean skin par twice use karna hai. cream ko sirf face par hi use karna hai.

Side Effects

Is combination se side effects ke chances jyada nai hai lekin kuch skin redness, infections, burns, swelling, irritation, aur skin dryness hoti hai, jese aap soreness aur itching mahsus karte hai.

Toxicity

Is combination ka use karne se koi hydroquinone related toxicity nai hota hai.

Precaution

Aapko is combination aur aapke skin dono ke liye important precautions lena hoga, jaise -

• Aapko sunscreen ka istemal karna hoga.
• Iska use kuch sensitive areas par avoid karna hai.
• Jab bhi cream use kare to aapko hands ko wash karke istemal karna hai.
• Iska use aapko pure face par hi karna hai nai kisi skin areas par nai
• Agar aapko any problem aati hai to aapko doctor se mile aur unhe problem bataye.

Interaction

Is combination ke saath aapko kisi bhi drug ke saath side effects nai hone dena hai na hi koi kind of disease interaction, drug interaction, aur food interaction hone dena chahiye.

Pregnancy Use

Is combination ka use pregnant woman ke saath kabhi bhi nai kare. iska istemal pregnant woman mai potentional risks badha sakta hai.

Lactation Use

Is combination ka use aap kisi bhi nursing mother mai nai kare.

Acute Overdose

Aapko is combination ka overdose nai karna hai. iske overdose se aapko aarambh sehi nai mil sakte.

Contraindication

Is combination ko kabhi bhi sun tan, rosacea, warts, aur injuries skin par use nai karna.

Use Direction

Is combination ko aapko roz twice use karna hoga - subah aur raat ko. cream ko sirf face par hi use kare.

Storage Condition

Is combination ko cool place par save store karke rakhna hai. iska temperature 25-30°C hona chahiye.

Volume of Distribution

Hydroquinone ka Volume of Distribution 17L/kg, Mometasone Furoate ka Volume of Distribution 3.8L/kg aur Tretinoin ka Volume of Distribution 10.6L/kg hai.

Half Life

Hydroquinone ka Half Life 60 minutes hai, Mometasone Furoate ka Half Life 9.4 hours hai aur Tretinoin ka Half Life 20-40 hours hai.

Clearance

Hydroquinone ka Clearance 0.865ml/min/kg hai, Mometasone Furoate ka Clearance 3ml/min/kg aur Tretinoin ka Clearance 0.2ml/min/kg hai.

Here you find in details version of Hydroquinone + Mometasone Furoate + Tretinoin